Using Canonical Correlation Analysis to Discover Genetic Regulatory Variants
نویسندگان
چکیده
منابع مشابه
Using Canonical Correlation Analysis to Discover Genetic Regulatory Variants
BACKGROUND Discovering genetic associations between genetic markers and gene expression levels can provide insight into gene regulation and, potentially, mechanisms of disease. Such analyses typically involve a linkage or association analysis in which expression data are used as phenotypes. This approach leads to a large number of multiple comparisons and may therefore lack power. We assess the...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2010
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0010395